Publications

A peer-reviewed
scientific foundation

Selected work underpinning the molecular architecture, membrane interaction, and the preclinical promise of bottlebrush macromolecules.

2025PNAS

Synthetic bottlebrush block copolymer prevents disease onset in Duchenne muscular dystrophy

Cohen, H.; Angulski, A.B.B.; Quick, J.D.; Kuebler, T.; Thompson, B.R.; et al.

122 (42), e2513599122
2023Langmuir

Discovery of kinetic trapping of poloxamers inside liposomes via thermal treatment

Hassler, J.; Lawson, M.; Arroyo, E.; Bates, F.S.; Hackel, B.J.; Lodge, T.P.

39, 14263–14274
2023Biomacromolecules

Effect of bottlebrush poloxamer architecture on binding to liposomes

Hassler, J.; Crabtree, A.A.; Liberman, L.; Bates, F.S.; Hackel, B.J.; Lodge, T.P.

24, 449–461
2022ACS Macro Letters

Synthesis and micellization of bottlebrush poloxamers

Hassler, J.F.; Van Zee, N.J.; Crabtree, A.A.; Bates, F.S.; Hackel, B.J.; Lodge, T.P.

11, 460–467

Publications describe research conducted by academic investigators and collaborators. Findings from preclinical models may not translate to humans.